Experiencing any of these reactions is enough to make anyone depressed. But what about the social isolation? Consider those who have to move multiple times in a movie theatre only to have to finally leave because someone’s perfume is making them sick. Same in a restaurant or church. Many people have to change their daily activities to avoid multiple triggers, both at work and at home, that may mildly to severely affect them. There are people who actually have to wear a face mask when they leave their homes. Give that a try. Sounds depressing doesn’t it?